Chevron

Made in France 🇫🇷

Free Shipping Over $50

90 Years of Pharmaceutical Expertise You Can Trust

Save 20% on your first order!

Chevron

FEM by UPSA

Home Shop Products Rewards Program About Us Contact Information Our Science
United States USD Chevron
Account

When symptoms say Pause, FEM hits Play

Get the French supplement without hormones.

Shop Now

When symptoms say Pause, FEM hits Play

Get the French supplement without hormones.

Shop Now

Feel Like Yourself Again.

Hot flashes. Sleep disruption. Mood swings.

You don't have to accept these as your "new normal". Our patented core ingredient, CyTonin®, is a scientifically proven, non-hormonal supplement, ideal for women who cannot or choose not to use hormone therapy.

LEARN MORE

Perimenopause and menopause aren't endings. They're transitions into your most powerful chapter yet.

SHOP SOLUTIONS

Perimenopause and menopause aren't endings. They're transitions into your most powerful chapter yet.

SHOP SOLUTIONS

You've built careers, nurtured families, created impact, and shaped the world around you. Why should biology slow you down now?
World
Trusted by Women Worldwide
Eco
100% Vegetarian Formulas
Medal
Quality Guaranteed, Patented Technology
Pen and ruler
Science-Backed & Clinically-Proven

Manage your symptoms

FIND THE SOLUTION THAT'S RIGHT FOR YOU. TAKE OUR QUIZ. Link chevron
FEM Perimeno
FEM Perimeno
From $39.99
FEM Meno
FEM Meno
From $42.99
FEM Urovital
FEM Urovital
$39.99

Our CyTonin® Technology; Where Nature Meets Science to Relieve Your Symptoms

FEM is based on Purified and Specific Cytoplasm Extracts of Swedish Pollen, using the proprietary and exclusive CyTonin® Technology. This removes the rigid and gastro-resistant shell of pollen grains and only the pollen cytoplasm is extracted, as it is the reservoir of many natural nutrients including proteins, vitamins, amino-acids, trace elements, fatty acids. 
Hot Flashes
Night Sweats
Sleep Disturbances
Mood Swings & Irritability
Fatigue & Low Energy
You're not slowing down. You're shifting gears.

Non-Hormonal. Effective. Safe.

Your body is changing. Our breakthrough formulas work with your body's natural processes—not against them.

Learn more
WHAT OUR CUSTOMERS SAY

Real Reviews from Real Women

IT WORKS! You've tried other types of food supplements, and this one really works. It has helped me with hot flushes and has also helped me sleep better. It's effective, 100% recommended.
Quote
Maria
United Kingdom

Absolutely brilliant supplement! Within weeks, my hot flushes and night sweats reduced significantly—natural, gentle, and truly effective. Would recommend.
Quote
Bethany
United Kingdom

I had unbearable hot flushes every 15 minutes. I couldn't even sleep. I started to see results the next day. After a month I had almost no hot flushes. Within the second month of using them, they completely disappeared.
Quote
Jane S.
France
WHY TRUST US?

⭐⭐⭐⭐⭐ Rated 4.5/5 in the UK. 300+ million doses sold globally.

Clinically proven to reduce hot flashes, night sweats, and fatigue in 2 months.
FEM Perimeno
FEM Perimeno
FEM Perimeno
FEM Perimeno
FEM Perimeno
Play
Settings
FEM Perimeno
FEM Perimeno
FEM Perimeno
FEM Perimeno
FEM Perimeno
Play
Settings
FEM by UPSA

FEM Perimeno

$39.99
Taxes and shipping calculated at checkout
SKU:
Amount
30-Day Supply
60-Day Supply
Amount
Many in stock

Effective, Proven Relief

From our natural, non-hormonal, doctor recommended formulas.
~62% of women have less night sweats*
~60% of women feel less irritated*
~50% of women have fewer sleep problems*
*Lachowsky M. et al., Evaluation of the quality of life, efficacy and tolerance of FEM/Sérelys® in women during perimenopause and menopause. Genesis, 2015; Volume 189: 10-13.
LEARN ABOUT PERIMENOPAUSE

DID YOU KNOW?

Perimenopause typically lasts 4-8 years, and can even extend up to 10 years or more for some women. We'll help you find the natural solution that's right for you.

TAKE THE QUIZ
LEARN ABOUT PERIMENOPAUSE

DID YOU KNOW?

Perimenopause typically lasts 4-8 years, and can even extend up to 10 years or more for some women. We'll help you find the natural solution that's right for you.

TAKE THE QUIZ

When your symptoms say "pause", FEM hits play.

URINARY TRACT HEALTH SUPPORT

The Safety You Need, The Results You Want: Non-Hormonal, Effective Relief.

SHOP NOW
URINARY TRACT HEALTH SUPPORT

The Safety You Need, The Results You Want: Non-Hormonal, Effective Relief.

SHOP NOW

Feel the Difference

Sleep disturbances are one of the most common symptoms of perimenopause and menopause. But, a good night's sleep is possible with Fem Perimeno and Fem Meno.

Learn More
Shield
CLEAN INGREDIENTS, RIGOROUS SCIENCE, QUALITY & SAFETY GUARANTEED

Made in France | Origine France Garantie

For 90 years, our parent company UPSA has been manufacturing its medicines in Agen, in the Lot-et-Garonne region.

UPSA is the first pharmaceutical laboratory certified Origine France Garantie for all of its medicines, including our FEM line. The Origine France Garantie certification is a mark of quality on the international stage, reflecting the heritage of our expertise and our capacity for innovation. Our manufacturing plants are located in:

  • Gascogne, France
  • Guyenne, France
  • La Plaine, France

Meet FEM Perimeno Link chevron
Meet FEM Meno Link chevron
Meet FEM Urovital Link chevron

Knowledge Center

What You Might Not Know About Perimenopause
perimenopause
Dec 16, 2025

What You Might Not Know About Perimenopause

Perimenopause remains one of the most misunderstood phases of a woman's life, often dismissed or confused with menopause itself. This transitional period deserves far more attention than it receives, as...
Read more
What You Might Not Know About Perimenopause
perimenopause
Dec 16, 2025

What You Might Not Know About Perimenopause

Perimenopause remains one of the most misunderstood phases of a woman's life, often dismissed or confused with menopause itself. This transitional period deserves far more attention than it receives, as...
Read more

Follow us on Instagram

Stay inspired with helpful info, ingredient deep dives, and limited-time offers.